To lower triglycerides naturally with supplements, consider taking 2-4 g of fish oil daily.
Fish oil supplements contain eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), two omega-3 fatty acids that have been shown to reduce triglycerides by up to 15-30 percent, with higher reductions seen in those with elevated triglycerides at baseline [1
While the American Heart Association recommends 1 g/day of EPA + DHA for cardioprotection, higher dosages of omega-3 fatty acids (2-4 g/day) are required to reduce elevated triglyceride levels [2
]. Taking up to 3-5 g (3,000–5,000 mg) of omega-3 per day appears to be safe. [3
Prescription fish oil contains more active fatty acids than many nonprescription supplements and may be more beneficial if you have very high triglycerides. Research shows that taking the prescription drug Vascepa, which contains pure EPA, helps lower triglyceride levels by up to 33% [5