Should vitamins D, E and K be taken together?

This question is about Nutrition

Sarah Achleithner

Some evidence suggests that moderate to large doses of vitamins D, E, and K may reduce absorption when taken together. The absorption of vitamin K seems to be most affected in the presence of other fat-soluble vitamins [1]. Take these supplements at least two hours apart and with some sort of dietary fat to optimize absorption.

yellow supplements in one hand


  1. Goncalves, A., Roi, S., Nowicki, M., Dhaussy, A., Huertas, A., Amiot, M.-J., & Reboul, E. (2015). Fat-soluble vitamin intestinal absorption: Absorption sites in the intestine and interactions for absorption. Food Chemistry, 172, 155–160.