The 7 best joint health supplements, according to science

If you’re struggling with inflammation, joint pain, or extreme stiffness, certain supplements may provide some relief. From omega-3s to vitamin C, here are the best science-backed joint health supplements to consider adding to your routine.

Maintaining optimal joint health is essential for leading an active and fulfilling life. Your joints, which connect bones and allow for movement, are subject to wear and tear over time, leading to discomfort, stiffness, and reduced mobility. As a result, the popularity of joint health supplements has skyrocketed, offering a promising solution to alleviate joint-related issues.

Joint health supplements encompass a wide range of products, including vitamins, minerals, herbs, and other natural substances that aim to support joint function, reduce inflammation, and promote overall joint well-being. But are these supplements truly beneficial, and who stands to gain the most from their usage?

Before diving into the research on joint health supplements, let’s first understand what you should look for in supplementation and if you should consider adding them to your routine.

Are joint health supplements beneficial?

Joint pain can affect anyone, but especially athletes, individuals older than 60 years old, women, or those who have arthritis. 

In addition to making lifestyle and dietary changes to promote healthy joints (such as doing weight-bearing exercises and eating an anti-inflammatory diet rich in protein), supplementation may also be beneficial, especially for people who are experiencing joint discomfort, COVID joint pain, or are at risk of developing joint issues. 

Some evidence suggests supplements like glucosamine, omega-3 fatty acids, curcumin, and vitamin C can support joint health by reducing inflammation and alleviating symptoms of related conditions such as osteoarthritis.

Below we break down the best science-backed joint health supplements worth considering. If you choose to take joint health supplements, look for ones that have been

third-party tested

to ensure you’re getting the highest quality possible.

Disclaimer: Supplements aren’t a magic potion for making joint pain disappear or to be used as a substitute for chronic pain medication. To see if joint health supplements are right for you, talk with your healthcare provider before adding anything new to your routine. 

Product Supplements Image5 2x (1)

Personalized supplements with Elo Health

At

Elo Health

, we offer

1:1 dietitian support

so you can stay accountable, reach your health and fitness goals, and better understand your health. For example, if you’re looking to improve joint health, a Registered Dietitian can create a health plan for you that focuses on certain supplements and will be able to work with you on lifestyle topics like stress management, athletic performance, weight loss, energy, and more. 

Elo also provides

personalized smart supplements

made just for you through

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,

biomarkers

, and data from wearables. After all, your nutrition needs are unique, and your supplement plan should be, too.

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Protein

Protein

is an essential macronutrient composed of 20 different amino acids, nine of which are considered “essential” because your body cannot produce them and, therefore, must come from your diet. These 20 amino acids are considered the primary building blocks of your body since they are found in tissues (including organs, bones, muscles, tendons, cartilage, ligaments, and skin), hormones, enzymes, red blood cells, and more.

Research continues to show the importance of this crucial macronutrient, as it’s been found to promote the repair and growth of muscle tissue, prevent injury, and promote overall strength [

1

]. This is especially important for joint health, as muscle strength may protect joints from excessive wear and tear.

Protein can also be beneficial for maintaining muscle mass loss that comes with aging or osteoarthritis. One study found that people with osteoarthritis who took a protein supplement experienced improvements in muscle mass and strength, reduced pain, better physical mobility, and better global functioning compared to those who didn’t supplement [

2

]. 

Dosing recommendations

The current RDA is 0.8 g protein/kg of body weight/day (g/kg/day) for all adults over 18 years of age, including elderly adults over the age of 65 [

3

]. However, studies also indicate that people over 65 years old may benefit from higher intakes of 1 to 1.2 g/kg/day [

4

]. 

If you are an athlete or highly active individual, research shows that you may need 1.2-2.0 g/kg/day, depending on training needs and goals [

5

]. 

toan post workout packaging

Elo Smart Protein and post-workout recovery

Elo Smart Protein

is a personalized protein powder that is designed for anyone who wants to boost recovery and enhance performance. Unlike other custom protein products, Elo Smart Protein uses your goals, health history, workout data, and dietary preferences to craft the right protein blend for you and provide specific protein dosing recommendations after every workout. 

Elo Smart Protein is also backed by the latest science to help you recover faster and get the most out of every scoop of protein powder.

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collagen powder

Collagen

Collagen

is the most abundant protein in the human body and is the main component of connective tissues (like skin, bone, tendons, ligaments, and cartilage) that provides structure, support, and protection throughout the body [

6

]. Learn more about the different types of collagen

here

.

As you age, your body naturally loses collagen, which may increase your risk of degenerative joint disorders such as osteoarthritis [

7

]. However, some research shows collagen supplementation may help improve symptoms of osteoarthritis, as well as potentially reduce pain and inflammation, joint stiffness, and the risk of joint deterioration in athletes [

8

,

9

]. 

Dosing recommendations

Research shows that taking 2.5–15 g of hydrolyzed collagen peptides/day may be safe and effective; however, the amount of collagen you should take depends on the particular supplement and why you’re taking it [

10

]. 

For instance, studies have found doses of 10 g/day of hydrolyzed collagen or 10-40 mg/day of undenatured type II collagen may be beneficial for reducing joint pain associated with osteoarthritis as well as exercise-related joint pain in active adults [

8

,

9

,

11

]. 

Precautions

While most people can safely take collagen, individuals with allergies to meat, fish, shellfish, and eggs should avoid collagen supplements made with these ingredients. 

Additionally, you may want to hold off on taking a collagen supplement if you’re pregnant or breastfeeding since there isn’t enough research on whether or not they’re safe in these populations [

12

]. 

orange slice half filled with white pills

Vitamin C

Also known as L-ascorbic acid,

vitamin C

is an antioxidant that is necessary for collagen synthesis. It’s also involved with protein metabolism and may help to prevent or delay the development of cardiovascular disease and certain cancers [

13

]. 

Furthermore, emerging evidence shows that vitamin C plays a role in bone health, as it has the potential to accelerate bone healing after a fracture, increase type I collagen synthesis, boost bone density, and reduce oxidative stress parameters [

14

,

15

,

16

]. 

Since your body doesn't naturally produce vitamin C, it’s necessary to obtain it through certain foods and supplements.  

Dosing recommendations

The recommended daily amount (RDA) for adults is as follows [

13

]: 

  • Men and women 9–13 years old: 45 mg/day

  • Men 14-18 years old: 75 mg/day

  • Women 14-18 years old: 65 mg/day, with this number increasing to 80 mg/day and 115 mg/day for pregnant and lactating women, respectively. 

  • Men over 19 years old: 90 mg/day

  • Women over 19 years old: 75 mg/day, with this number increasing to 85 mg/day and 120 mg/day for pregnant and lactating women, respectively. 

  • People who smoke: an additional 35 mg/day than nonsmokers.

Precautions

While many people can tolerate vitamin C, you should talk with your healthcare provider about taking it since it may cause specific drug-nutrient interactions, increase cardiovascular disease risk, or negatively affect iron stores for those with hemochromatosis [

17

,

18

,

19

].  

Ground turmeric in a spoon

Turmeric and curcumin

Turmeric

is a bright yellow spice made from the root of the Curcuma longa plant. Curcumin is a naturally occurring compound in turmeric that gives this spice its bright yellow color and potent anti-inflammatory properties. 

Since curcumin has strong anti-inflammatory properties, evidence suggests it can alleviate symptoms of osteoarthritis, improve joint function, and reduce pain and inflammation [

20

,

21

]. 

Dosing recommendations

You can obtain curcumin through a turmeric supplement. While there is no standard dose for turmeric, the World Health Organization has established 1.4 mg of curcumin/pound of body weight (0–3 mg/kg) as an acceptable daily intake [

22

]. 

Precautions

It’s strongly advised to avoid turmeric supplements if you are pregnant, breastfeeding, have certain conditions (like diabetes, gallstones, gallbladder or kidney disease, bleeding disorders, or immunity problems), have an upcoming surgery, or are taking certain medications.

vegan omega-3 food sources

Omega-3s

Omega-3 fatty acids

are polyunsaturated fats vital to cell membranes and other body functions. Because your body can’t naturally produce them, omega-3s are considered to be essential nutrients that must be consumed through diet and supplements. 

While these fatty acids are incredibly beneficial for overall health, studies also show that omega-3s are crucial for joint health, as they can reduce swelling and joint tenderness, allow for a better range of motion after exercise, reduce strength loss, and modulate disease activity in rheumatoid arthritis [

23

,

24

]. 

Dosing recommendations

The daily recommendation for all omega-3s is 1,600 mg/day for men and 1,100 mg/day for women [

25

]. 

Precautions

If you have high triglycerides, it may be best to avoid omega-3 supplements, as they have been associated with an increased likelihood of developing atrial fibrillation.

tart cherry juice

Tart cherry juice

Tart cherry juice

(made from the fruit of the Prunus cerasus tree) is a rich source of antioxidants, nutrients, and beneficial plant compounds. It has also been found to help minimize inflammation, post-exercise muscle pain, and muscle soreness [

26

]. 

Studies suggest that daily consumption of tart cherry juice may result in better mobility, relief of pain-related symptoms and quality of life, and selective markers of cartilage health [

27

]. 

Dosing recommendations

While the timing and dosage can widely vary, most studies have found that consuming 8-12 oz of tart cherry juice extract twice a day can promote recovery [

28

]. 

Precautions

Because tart cherry juice contains quercetin, it may negatively interact with certain medications, such as blood thinners. Consult a healthcare professional before adding this supplement to your diet [

29

,

30

]. 

Glucosamine

Glucosamine is an amino sugar compound that is found in cartilage, the tough tissue that cushions your joints [

31

]. 

While it’s most often used to treat pain caused by inflammation and osteoarthritis, studies indicate that glucosamine may also help prevent cartilage breakdown which can be common among endurance athletes [

32

,

33

]. Furthermore, research shows that glucosamine may help improve knee mobility after injuries, reduce pain, and improve joint function [

34

,

35

]. 

Dosing recommendations

If you choose to supplement with glucosamine, research suggests 300 – 500 mg three times a day for a total daily dose of 900 – 1,500 mg. While preliminary evidence shows you could slow joint degradation by taking doses as high as 3,000 mg of glucosamine, this may be the most relevant for athletes competing in high-impact sports, like running [

36

].

Precautions

While glucosamine is generally safe to take, you may want to avoid this supplement if you have shellfish allergies, have glaucoma, or take warfarin (Coumadin) or acetaminophen (such as Tylenol) [

37

,

38

]. 

Summary

Joint health is important because joints play a crucial role in your body's mobility and overall functionality. Over time, your joints are subject to wear and tear, which can cause discomfort, stiffness, and reduced range of motion. While athletes, older adults, women, and those with arthritis are more prone to joint pain, this condition can affect anyone at any stage. 

You can improve joint health with certain lifestyle and dietary changes. Still, some supplements like protein, collagen, vitamin C, curcumin, omega-3 fatty acids, tart cherry juice, and glucosamine may also improve inflammatory markers and reduce exercise-related joint pain.

If you’re confused about which ones are right for you,

Elo Health

can help. We determine the right joint health supplements for you based on your biomarkers and wearable data so you can reach your goals. 

Disclaimer: The text, images, videos, and other media on this page are provided for informational purposes only and are not intended to treat, diagnose, or replace personalized medical care.

Key takeaways

  • Protein, collagen, vitamin C, curcumin, omega-3 fatty acids, tart cherry juice and glucosamine are supplements that may improve inflammatory markers, reduce exercise-related joint pain, and alleviate symptoms of conditions such as osteoarthritis.

  • In addition to taking supplements, you can

    reduce inflammation

    and protect your joints through certain lifestyle and dietary changes (such as doing weight-bearing exercises and eating an anti-inflammatory diet rich in protein). 

  • Elo Health

    offers personalized supplements to address your specific health and wellness concerns. 

  • Supplements are not created equal, and may not be recommended for everyone. To see if a supplement is right for you, talk with your healthcare provider before adding anything new to your routine.

References

  1. Pasiakos, S. M., McLellan, T. M., & Lieberman, H. R. (2015). The effects of protein supplements on muscle mass, strength, and aerobic and anaerobic power in healthy adults: a systematic review. Sports medicine (Auckland, N.Z.), 45(1), 111–131.

    https://doi.org/10.1007/s40279-014-0242-2

     

  2. Liao, C. D., Wu, Y. T., Tsauo, J. Y., Chen, P. R., Tu, Y. K., Chen, H. C., & Liou, T. H. (2020). Effects of Protein Supplementation Combined with Exercise Training on Muscle Mass and Function in Older Adults with Lower-Extremity Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Trials. Nutrients, 12(8), 2422.

    https://doi.org/10.3390/nu12082422

     

  3. Baum, J. I., Kim, I. Y., & Wolfe, R. R. (2016). Protein Consumption and the Elderly: What Is the Optimal Level of Intake?. Nutrients, 8(6), 359.

    https://doi.org/10.3390/nu8060359

     

  4. Bauer, J., Biolo, G., Cederholm, T., Cesari, M., Cruz-Jentoft, A. J., Morley, J. E., Phillips, S., Sieber, C., Stehle, P., Teta, D., Visvanathan, R., Volpi, E., & Boirie, Y. (2013). Evidence-based recommendations for optimal dietary protein intake in older people: A position paper from the Prot-Age Study Group. Journal of the American Medical Directors Association, 14(8), 542–559.

    https://doi.org/10.1016/j.jamda.2013.05.021

     

  5. Carbone, J. W., & Pasiakos, S. M. (2019). Dietary protein and muscle mass: Translating science to application and Health Benefit. Nutrients, 11(5), 1136.

    https://doi.org/10.3390/nu11051136

     

  6. Physiology, Connective Tissue. (n.d.).

    https://www.ncbi.nlm.nih.gov/books/NBK542226/

     

  7. Li, Y.-S., Xiao, W., & Luo, W. (2017). Cellular aging towards osteoarthritis. Mechanisms of Ageing and Development, 162, 80–84.

    https://doi.org/10.1016/j.mad.2016.12.012

     

  8. García-Coronado, J. M., Martínez-Olvera, L., Elizondo-Omaña, R. E., Acosta-Olivo, C. A., Vilchez-Cavazos, F., Simental-Mendía, L. E., & Simental-Mendía, M. (2018). Effect of collagen supplementation on osteoarthritis symptoms: A meta-analysis of randomized placebo-controlled trials. International Orthopaedics, 43(3), 531–538.

    https://doi.org/10.1007/s00264-018-4211-5

     

  9. Clark, K. L., Sebastianelli, W., Flechsenhar, K. R., Aukermann, D. F., Meza, F., Millard, R. L., Deitch, J. R., Sherbondy, P. S., & Albert, A. (2008). 24-week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Current Medical Research and Opinion, 24(5), 1485–1496.

    https://doi.org/10.1185/030079908x291967

     

  10. Paul, C., Leser, S., & Oesser, S. (2019). Significant amounts of functional collagen peptides can be incorporated in the diet while maintaining indispensable amino acid balance. Nutrients, 11(5), 1079.

    https://doi.org/10.3390/nu11051079

     

  11. Lugo, J. P., Saiyed, Z. M., & Lane, N. E. (2015). Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: A multicenter randomized, double-blind, placebo-controlled study. Nutrition Journal, 15(1).

    https://doi.org/10.1186/s12937-016-0130-8

     

  12. WebMD. (n.d.). Collagen peptides: Overview, uses, side effects, precautions, interactions, dosing and reviews. WebMD.

    https://www.webmd.com/vitamins/ai/ingredientmono-1606/collagen-peptides

     

  13. U.S. Department of Health and Human Services. (n.d.). Office of dietary supplements - vitamin C. NIH Office of Dietary Supplements.

    https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/

     

  14. Chin, K. Y., & Ima-Nirwana, S. (2018). Vitamin C and Bone Health: Evidence from Cell, Animal and Human Studies. Current drug targets, 19(5), 439–450.

    https://doi.org/10.2174/1389450116666150907100838

     

  15. DePhillipo, N. N., Aman, Z. S., Kennedy, M. I., Begley, J. P., Moatshe, G., & LaPrade, R. F. (2018). Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review. Orthopaedic journal of sports medicine, 6(10), 2325967118804544.

    https://doi.org/10.1177/2325967118804544

     

  16. American Bone Health. (2020, February 6). Vitamins for bone health. American Bone Health.

    https://americanbonehealth.org/nutrition/vitamins-for-bone-health/

     

  17. Drug-nutrient interactions. Linus Pauling Institute. (2022, July 6).

    https://lpi.oregonstate.edu/mic/drug-nutrient-interactions

     

  18. Moser, M. A., & Chun, O. K. (2016). Vitamin C and Heart Health: A Review Based on Findings from Epidemiologic Studies. International journal of molecular sciences, 17(8), 1328.

    https://doi.org/10.3390/ijms17081328

     

  19. Dietary guidelines for hemochromatosis - university of virginia school ... (n.d.-a).

    https://med.virginia.edu/ginutrition/wp-content/uploads/sites/199/2021/01/Hemochromatosis-2017.pdf

     

  20. Examine.com. (2023, March 21). Curcumin health benefits, dosage, safety, side-effects, and more: Supplements. Examine.

    https://examine.com/supplements/curcumin/

     

  21. Paultre, K., Cade, W., Hernandez, D., Reynolds, J., Greif, D., & Best, T. M. (2021). Therapeutic effects of turmeric or curcumin extract on pain and function for individuals with knee osteoarthritis: a systematic review. BMJ open sport & exercise medicine, 7(1), e000935.

    https://doi.org/10.1136/bmjsem-2020-000935

     

  22. Amalraj, A., Pius, A., Gopi, S., & Gopi, S. (2017). Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives – a review. Journal of Traditional and Complementary Medicine, 7(2), 205–233.

    https://doi.org/10.1016/j.jtcme.2016.05.005

     

  23. Kostoglou-Athanassiou, I., Athanassiou, L., & Athanassiou, P. (2020). The Effect of Omega-3 Fatty Acids on Rheumatoid Arthritis. Mediterranean journal of rheumatology, 31(2), 190–194.

    https://doi.org/10.31138/mjr.31.2.190

     

  24. Tsuchiya, Y., Yanagimoto, K., Nakazato, K., Hayamizu, K., & Ochi, E. (2016). Eicosapentaenoic and docosahexaenoic acids-rich fish oil supplementation attenuates strength loss and limited joint range of motion after eccentric contractions: a randomized, double-blind, placebo-controlled, parallel-group trial. European journal of applied physiology, 116(6), 1179–1188.

    https://doi.org/10.1007/s00421-016-3373-3

     

  25. U.S. Department of Health and Human Services. (n.d.-a). Office of dietary supplements - omega-3 fatty acids. NIH Office of Dietary Supplements.

    https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/

     

  26. Kuehl, K. S., Perrier, E. T., Elliot, D. L., & Chesnutt, J. C. (2010). Efficacy of tart cherry juice in reducing muscle pain during running: a randomized controlled trial. Journal of the International Society of Sports Nutrition, 7, 17.

    https://doi.org/10.1186/1550-2783-7-17

     

  27. Du, C., Chapman, S. C., Kwon, Y. H., Vijayagopal, P., & Juma, S. (2019). Impact of Tart Cherry Juice on Joint Flexibility and Pain in Individuals with Self-Reported Knee Osteoarthritis (P01-030-19). Current Developments in Nutrition, 3(Suppl 1), nzz028.P01-030-19.

    https://doi.org/10.1093/cdn/nzz028.P01-030-19

     

  28. Vitale, K. C., Hueglin, S., & Broad, E. (2017). Tart Cherry Juice in Athletes: A Literature Review and Commentary. Current sports medicine reports, 16(4), 230–239.

    https://doi.org/10.1249/JSR.0000000000000385

     

  29. Kim, D. W., Jung, D. H., Sung, J., Min, I. S., & Lee, S. J. (2021). Tart Cherry Extract Containing Chlorogenic Acid, Quercetin, and Kaempferol Inhibits the Mitochondrial Apoptotic Cell Death Elicited by Airborne PM10 in Human Epidermal Keratinocytes. Antioxidants (Basel, Switzerland), 10(3), 443.

    https://doi.org/10.3390/antiox10030443

     

  30. Andres, S., Pevny, S., Ziegenhagen, R., Bakhiya, N., Schäfer, B., Hirsch-Ernst, K. I., & Lampen, A. (2018). Safety Aspects of the Use of Quercetin as a Dietary Supplement. Molecular nutrition & food research, 62(1), 10.1002/mnfr.201700447.

    https://doi.org/10.1002/mnfr.201700447

     

  31. National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 439213, D-Glucosamine. Retrieved June 8, 2023 from

    https://pubchem.ncbi.nlm.nih.gov/compound/D-Glucosamine

    .

  32. Jerosch J. (2011). Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids. International journal of rheumatology, 2011, 969012.

    https://doi.org/10.1155/2011/969012

     

  33. Nagaoka, I., Tsuruta, A., & Yoshimura, M. (2019). Chondroprotective action of glucosamine, a chitosan monomer, on the joint health of athletes. International journal of biological macromolecules, 132, 795–800.

    https://doi.org/10.1016/j.ijbiomac.2019.03.234

     

  34. Ostojic, S. M., Arsic, M., Prodanovic, S., Vukovic, J., & Zlatanovic, M. (2007). Glucosamine administration in athletes: effects on recovery of acute knee injury. Research in sports medicine (Print), 15(2), 113–124.

    https://doi.org/10.1080/15438620701405248

     

  35. Ogata, T., Ideno, Y., Akai, M., Seichi, A., Hagino, H., Iwaya, T., Doi, T., Yamada, K., Chen, A. Z., Li, Y., & Hayashi, K. (2018). Effects of glucosamine in patients with osteoarthritis of the knee: a systematic review and meta-analysis. Clinical rheumatology, 37(9), 2479–2487.

    https://doi.org/10.1007/s10067-018-4106-2

     

  36. Examine.com. (2022, September 28). Glucosamine health benefits, dosage, safety, side-effects, and more: Supplements. Examine.

    https://examine.com/supplements/glucosamine

     

  37. U.S. Department of Health and Human Services. (n.d.). Glucosamine and chondroitin for osteoarthritis. National Center for Complementary and Integrative Health.

    https://www.nccih.nih.gov/health/glucosamine-and-chondroitin-for-osteoarthritis

     

  38. Mayo Foundation for Medical Education and Research. (2020, November 12). Glucosamine. Mayo Clinic.

    https://www.mayoclinic.org/drugs-supplements-glucosamine/art-20362874